Bulk Drug: Hypertension

Bulk Drug: Hypertension

Note

We just produce and sale these products as chemical products. If you use it as pharmaceutical ingredientes, you should test it and look whether it is meet your standard.

1.Atacand (Candesartan Cilexetil)
Chemical Name: (+- -1-[[(cyclohexyloxy)carbonyl]oxy]ethyl 2-ethoxy-1-[[2'-(1H-tetrazol-5-yl)[1,1'-biphenyl]
-4-yl]methyl]-1H-benzimidazole-7-carboxylate
CAS NO.: [145040-37-5]
Structural Formula: C₃₃H₃₄N₆O₆
Molecular Formula:

Molecular Weight: 610.67
Appearance: a white to off- white powder
Solubility: It is practically insoluble in water and sparingly soluble in methanol
Melting point:C
Residue on ignition: 0.5% max
Loss on drying: 0.3% max
Assay: 99% min
Heavy metal: 20 ppm max
Uses: Candesartan is a selective AT1 subtype angiotensin II receptor antagonist. It is indicated for the treatment of hypertension. It may be used alone or in combination with other antihypertensive agents
Packing: Aluminium or iron tin lined with plastic bag.

2. Irbesartan
Chemical Name: 2-butyl-3-[[ 29-( 1H-tetrazol-5-yl) [1, 19-biphenyl]-4-yl] methyl]1,3-diazaspiro[4,4] non-1-en-4-one
CAS NO.: [138402-11-6]
Structural Formula: C₂₅H₂₈N₆O
Molecular Formula:

Molecular Weight: 428.54
Appearance: a white to off- white powder
Solubility: Irbesartan is slightly soluble in alcohol and methylene chloride and practically insoluble in water.
Melting point: 180-182C
Residue on ignition: 0.5% max
Loss on drying: 0.3% max
Assay: 99% min
Heavy metal:
Uses: Irbesartan is a selective AT1 subtype angiotensin II receptor antagonist. It is indicated for the treatment of hypertension. It may be used alone or in combination with other antihypertensive agents
Packing: Aluminium or iron tin lined with plastic bag.

3. Valsartan
Chemical Name: N-(1-oxopentyl)-N-[[2´-(1H-tetrazol-5-yl)[1,1´-biphenyl]-4-yl]methyl]-L-valine
CAS NO.: [137862-53-4]
Structural Formula:

Molecular Formula: C₂₄H₂₉N₅O₃
Molecular Weight: 435.5
Appearance: White crystal.
Solubility: It is soluble in ethanol and methanol and slightly soluble in water
Melting point: 107-112C.
Specific Rotation [a]20D: -65 DEG to -70 DEG
Assay: 98% min
Heavy metal: 20 ppm max
Uses: It is a selective AT1 subtype angiotensin II receptor antagonist. It is indicated for the treatment of hypertension. It may be used alone or in combination with other antihypertensive agents.
Packing: Aluminium or iron tin lined with plastic bag.

4. Losartan potassium
Chemical Name: 2-butyl-4-chloro-1-[p-(o-1H-tetrazol-5-ylphenyl)benzyl]imidazole-5- methanol monopotassiurn
CAS NO.: [12475-99-8]
Structural Formula:

Molecular Formula: C₂₂H₂₂ClKN₆O
Molecular Weight: 461.01
Appearance: White crystal.
Solubility: It is freely soluble in water, soluble in alcohols, and slightly soluble in common organic solvents, such as acetonitrile and methyl ethyl ketone
Melting point:182-185 C.
Assay: 98% min
Heavy metal: 20 ppm max
Uses: It is a selective AT1 subtype angiotensin II receptor antagonist. It is indicated for the treatment of hypertension. It may be used alone or in combination with other antihypertensive agents.
Packing: Aluminium or iron tin lined with plastic bag.

5. Telmisartan
Chemical Name: 4'-[(1,4'-dimethyl-2'-propyl[2,6'-bi-1H-benzimidazol]-1'-yl)methyl]-[1,1'-biphenyl]-2-carboxylic acid
CAS NO.: [144701-48-4]
Structural Formula:

Molecular Formula: C₂₂H₂₂ClKN₆O
Molecular Weight: 514.63
Appearance: White crystal.
Solubility: . It is practically insoluble in water and in the pH range of 3 to 9, sparingly soluble in strong acid (except insoluble in 17 hydrochloric acid), and soluble in strong base
Melting point: C.
Assay: 98% min
Heavy metal: 20 ppm max
Uses: It is a selective AT1 subtype angiotensin II receptor antagonist. It is indicated for the treatment of hypertension. It may be used alone or in combination with other antihypertensive agents.
Packing: Aluminium or iron tin lined with plastic bag.

6. Olmesartan medoxomil (CS-866DM, CS-866, Olmetec, Benicar, Benevas)
Chemical Name:4-(1-Hydroxy-1-methylethyl)-2-propyl-1-[2'-(1H-5-tetrazolyl)biphenyl-4-ylmethyl]imidazole-5-carboxylic acid 5-methyl-2-oxo-1,3-dioxol-4-ylmethyl ester
CAS NO.: [144689-63-4]
Structural Formula:

Molecular Formula: C₂₉H₃₀N₆O₆
Molecular Weight: 558.599
Appearance: White crystal.
Solubility: . It is practically insoluble in water and in the pH range of 3 to 9, sparingly soluble in strong acid (except insoluble in 17 hydrochloric acid), and soluble in strong base
Melting point: C.
Assay: 98% min
Heavy metal: 20 ppm max
Uses: CARDIOVASCULAR DRUGS, Diabetic Nephropathy, Agents for, ENDOCRINE DRUGS, Hypertension, Treatment of, Treatment of Diabetic Complications, Angiotensin AT1 Antagonists
Packing: Aluminium or iron tin lined with plastic bag.

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